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Acetaminophen / butalbital / caffeine
Brand Name: Fioricet
Most Common Medical Uses
Acetaminophen is a pain reliever and fever reducer. Butalbital is in a class of drugs called barbiturates that slow down your central nervous system (brain and nerve impulses) causing relaxation. Caffeine is
believed to constrict dilated blood vessels that may contribute to tension headaches. Together, acetaminophen, butalbital, and caffeine are used to relieve complex tension (muscle contraction) headaches although precisely how it works is unknown. Acetaminophen / butalbital / caffeine
may also be used for purposes other than those listed in this medication guide.
How to Take This Medication
Take acetaminophen / butalbital / caffeine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full
glass of water. Take acetaminophen / butalbital / caffeine with food or milk if it upsets your stomach. Never take more acetaminophen / butalbital / caffeine than is prescribed for you. If your pain is not being adequately treated, talk to your doctor.
Possible Side Effects
If you experience any of the following serious side effects, stop taking acetaminophen / butalbital / caffeine and seek emergency medical attention: an allergic reaction (difficulty breathing; closing of your
throat; swelling of your lips, tongue, or face; or hives); slow, weak breathing; liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue); blood problems (easy or unusual bleeding or bruising); or low blood sugar
(fatigue, increased hunger or thirst, dizziness, or fainting). These side effects are very rare and are not likely to occur during proper treatment with acetaminophen and caffeine. If you experience any unusual reactions, stop taking this medicine and seek the advice of your doctor.
Other, less serious side effects may be more likely to occur. Continue to take acetaminophen / butalbital / caffeine and talk to your doctor if you experience drowsiness; dizziness,, confusion or lightheadedness; shortness of breath; dry mouth; nausea, vomiting, abdominal pain, or
decreased appetite; tiredness, leg pain, or muscle weakness; agitation, irritability, nervousness, anxiety or excitability; rash or itching; feeling of intoxication; headache; or constipation.
Precautions
Use caution when driving, operating machinery, or performing other hazardous activities. Butalbital will cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these activities. Avoid
sleeping pills, antihistamines, sedatives, and tranquilizers except under the supervision of your doctor. These may also make you drowsy. Avoid alcohol. Alcohol taken during therapy with acetaminophen and butalbital can be very damaging to your liver and can increase drowsiness and
dizziness. Check the acetaminophen content of other over-the-counter and prescription products while taking this medication. You should not exceed 4 grams (4000 mg) of acetaminophen per day.
Drug Interactions
Do not take acetaminophen / butalbital / caffeine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days.
Dangerous side effects could result. Acetaminophen and butalbital may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), other pain relievers, anxiety medicines, and muscle relaxants. Tell
your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves. Many other medicines contain acetaminophen, especially over-the-counter pain, fever, cold, and allergy medications. Too much acetaminophen can be very dangerous. Drugs other
than those listed here may also interact with acetaminophen / butalbital / caffeine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Missed Dose
Take the missed dose as soon as you remember. Do not take a double dose of this medication. Wait the prescribed amount of time before taking your next dose.
Storage
Store at room temperature away from moisture and heat. Keep this and all medications out of the reach of children.
Notes
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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